Painkiller Jane is a planned live-action movie based on the independent comics of the same name created by Joe Quesada and Jimmy Palmiotti.
In 2016 Jessica Chastain became attached to star in the film. The next year Christine Boylan (The Punisher) was hired to write a screenplay.
Chastain would also produce with her producing partner Kelly Carmichael. Stephen L'Heureux of Solipsist Films is also a producer. Lenny Beckman is producing for Lotus Entertainment. Bill Johnson, Jim Seibel and Palmiotti are executive producers.